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Purpose: To retrospectively determine the distribution of stage I lung cancer growth rates with serial volumetric computed tomographic (CT) measurements. Materials and Methods: This study was institutional review board approved and HIPAA compliant. The informed consent requirement was waived. Patients ( n = 149) with stage I lung cancer who underwent two pretreatment CT examinations 25 or more days apart were identified. At the first and last examinations, tumor perimeters were manually inscribed by using software tools and the cross-sectional area was calculated. To calculate tumor volume, the summed areas were multiplied by the section increment and a formula was applied to reduce partial volume effects.

Doubling time (DT) was calculated by using the volume and interscanning interval. The percentages of tumors that would surpass volume increase thresholds of 5%–25% for detectable growth at different time intervals were calculated.

Age at diagnosis was compared with the reciprocal of DT, time interval between CT examinations, and initial tumor volume by using Pearson correlation. Download Virtual Girlfriend Jenny Apk Full Free. Elektroinstallation Symbols Pdf Writer here.

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